李贞（Li Zhen）
电子邮箱：zhenli@hubu.edu.cn 研究方向：上转换荧光生物分析 学 位：博士（武汉大学） 职 称：副教授/硕士生导师 职 务：无 |
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研究工作简介
李贞，博士，副教授，硕士生导师。主要从事上转换荧光生物分析等方面的研究工作。主持国家自然科学基金青年科学基金项目1项，省级人才。在JACS、J. Photochem. Photobio. C: Photochemistry Reviews、Anal. Chem.等国内外学术刊物上发表科研论文十余篇，其中SCI收录十余篇。
代表性成果
1. Xiaoxue Ye, Yunhui Xiang, Qirong Wang, Zhen Li*, Zhihong Liu*. A Red Emissive Two-Photon Fluorescence Probe Based on Carbon Dots for Intracellular pH Detection. Small, 2019, 1901637.
2. Tao Liang, Zhen Li*, Peipei Wang, Fangzhou Zhao, Jizhou Liu, Zhihong Liu*. Breaking Through the Signal-to-Background Limit of Upconversion Nanoprobes Using a Target-Modulated Sensitizing Switch. J. Am. Chem. Soc.2018, 140, 14696-14703.
3. Yuping Han, Lin Shen, Zhen Li*, Zhihong Liu*, A strategy to facilitate the assembly of DNA and upconversion nanoparticles for biosensor construction, Anal. Methods, 2018, 10, 3933-3938.
4. Zhen Li, Tao Liang, Songwei Lv, Qinggeng Zhuang, Zhihong Liu*. A rationally designed upconversion panoprobe for in vivo detection of hydroxyl radical. J. Am. Chem. Soc. 2015, 137, 11179-11185.
5. Zhen Li, Songwei Lv, Yali Wang, Shiyu Chen, Zhihong Liu*. Construction of LRET-based nanoprobe using upconversion nanoparticles with confined emitters and bared surface as luminophore. J. Am. Chem. Soc.2015, 137, 3421-3427.
6. Zhen Li, Mengyuan He, Dangdang Xu, Zhihong Liu*. Graphene materials-based energy acceptor systems and sensors. J. Photochem. Photobio. C: Photochemistry Reviews，2014, 18, 1-17.
7. Yuying Zhang, Zhen Li, Wei Hu, Zhihong Liu*. A Mitochondrial-Targeting Near-Infrared Fluorescent Probe for Visualizing and Monitoring Viscosity in Live Cells and Tissues. Anal. Chem. 2019, 91, 10302-10309.
8. Tao Liang, Zhen Li, Dan Song, Lin Shen, Qinggeng Zhuang, Zhihong Liu*. Modulating the luminescence of upconversion nanoparticles with heavy metal ions: a new strategy for probe design. Anal. Chem. 2016, 88, 9989-9995.
9. Mengyuan He, Zhen Li, Yiying Ge, Zhihong Liu*. Portable upconversion nanoparticles-based paper device for field testing of drug abuse. Anal. Chem. 2016, 88, 1530-1534.
10. Zhiqiang Mao, Hong Jiang, Zhen Li, Cheng Zhong, Wei Zhang, Zhihong Liu*, An N-nitrosation reactivity-based two-photon fluorescent probe for specific in situ detection of nitric oxide, Chem. Sci. 2017, 8, 4533-4538.
11. Zhiqiang Mao, Wenqi Feng, Zhen Li, Lingyu Zeng, Weijie Lv, Zhihong Liu*. NIR in, far-red out: developing a two-photon fluorescent probe for tracking nitric oxide in deep tissue. Chem. Sci. 2016, 7, 5230-5235.
